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All of life encodes information with DNA. While tools for sequencing, synthesis, and editing of genomic code have transformed biological research, intelligently composing new biological systems would also require a deep understanding of the immense complexity encoded by genomes.
This workshop will cover how NVIDIA RAPIDS offers a seamless experience to enable GPU-acceleration for many existing data science tasks with zero code changes. You will learn how to use GPU-accelerated tools to conduct data science faster, leading to more scalable, reliable, and cost-effective results!
This workshop will cover how NVIDIA RAPIDS offers a seamless experience to enable GPU-acceleration for many existing data science tasks with zero code changes. You will learn how to use GPU-accelerated tools to conduct data science faster, leading to more scalable, reliable, and cost-effective results!
Save the Date. Artificial intelligence is transforming how researchers collect, analyze, and learn from data. As AI systems become increasingly integrated into scientific discovery, business decision-making, and policy analysis, they are reshaping both the questions researchers can ask and the methods they use to answer them.
Save the Date. Artificial intelligence is transforming how researchers collect, analyze, and learn from data. As AI systems become increasingly integrated into scientific discovery, business decision-making, and policy analysis, they are reshaping both the questions researchers can ask and the methods they use to answer them.
We introduce Evo 2, a biological foundation model trained on 9.3 trillion DNA base pairs from a highly curated genomic atlas spanning all domains of life. We train Evo 2 with 7B and 40B parameters to have an unprecedented 1 million token context window with single-nucleotide resolution. Evo 2 learns from DNA sequence alone to accurately predict the functional impacts of genetic variation—from noncoding pathogenic mutations to clinically significant BRCA1 variants—without task-specific finetuning. Applying mechanistic interpretability analyses, we reveal that Evo 2 autonomously learns a breadth of biological features, including exon–intron boundaries, transcription factor binding sites, protein structural elements, and prophage genomic regions. Beyond its predictive capabilities, Evo 2 generates mitochondrial, prokaryotic, and eukaryotic sequences at genome scale with greater naturalness and coherence than previous methods. Guiding Evo 2 via inference-time search enables controllable generation of epigenomic structure, for which we demonstrate the first inference-time scaling results in biology. We make Evo 2 fully open, including model parameters, training code, inference code, and the OpenGenome2 dataset, to accelerate the exploration and design of biological complexity.
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