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Constitutive modeling and parameter identification are the cornerstones of realistic biomedical simulations. For decades, the gold standard in biomedical modeling has been to select a model and then fit its parameters to data. However, the scientific criteria for model selection remain poorly understood, and the success of this approach depends largely on user experience and personal preference.
How do AI agents influence knowledge work? This paper finds that agents shift worker effort from implementation to supervision, which especially benefits verifiable work and expert workers. I use data from the coding platform Cursor to study agents in software production.
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How do AI agents influence knowledge work? This paper finds that agents shift worker effort from implementation to supervision, which especially benefits verifiable work and expert workers. I use data from the coding platform Cursor to study agents in software production.
What does digital inclusion look like in the age of AI? Over 6,000 of the world’s 7,000-plus living languages remain digitally disadvantaged.
What does digital inclusion look like in the age of AI? Over 6,000 of the world’s 7,000-plus living languages remain digitally disadvantaged.
AI+Science: Accelerating Discovery is an interdisciplinary conference bringing together researchers across physics, mathematics, chemistry, biology, neuroscience, and more to examine how AI is reshaping scientific discovery.
AI+Science: Accelerating Discovery is an interdisciplinary conference bringing together researchers across physics, mathematics, chemistry, biology, neuroscience, and more to examine how AI is reshaping scientific discovery.
In this seminar, Kuhl proposes a new method that simultaneously and autonomously discovers the model, parameters, and experiment that best explain a wide variety of biological systems toward more realistic human simulations. She illustrates how we solve this problem by formulating it as a neural network, and leverage the success, robustness, and stability of state-of-the-art optimization tools from deep learning. Out of thousands of possible models, this network discovers a unique constitutive model that outperforms traditional models and, at the same time, identifies the best experiment to train itself. These new constitutive neural networks could initiate a paradigm shift in constitutive modeling—from user-defined model selection to automated model discovery— and forever change how we simulate biomedical systems.
