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Automated real-time assessment of intracranial hemorrhage detection AI using an ensembled monitoring model (EMM) | Stanford HAI

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research

Automated real-time assessment of intracranial hemorrhage detection AI using an ensembled monitoring model (EMM)

Date
October 13, 2025
Topics
Healthcare
Regulation, Policy, Governance
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abstract

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and unreliable AI predictions, which increases cognitive burden, reduces productivity, and potentially leads to misdiagnoses. To address these challenges, we introduce Ensembled Monitoring Model (EMM), a framework inspired by clinical consensus practices using multiple expert reviews. Designed specifically for black-box commercial AI products, EMM operates independently without requiring access to internal AI components or intermediate outputs, while still providing robust confidence measurements. Using intracranial hemorrhage detection as our test case on a large, diverse dataset of 2919 studies, we demonstrate that EMM can successfully categorize confidence in the AI-generated prediction, suggest appropriate actions, and help physicians recognize low confidence scenarios, ultimately reducing cognitive burden. Importantly, we provide key technical considerations and best practices for successfully translating EMM into clinical settings.

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Authors
  • Zhongnan Fang
    Zhongnan Fang
  • Andrew Johnston
    Andrew Johnston
  • Lina Cheuy
    Lina Cheuy
  • Hye Sun Na
    Hye Sun Na
  • Magdalini Paschali
    Magdalini Paschali
  • Camila Gonzalez
    Camila Gonzalez
  • Bonnie Armstrong
    Bonnie Armstrong
  • Arogya Koirala
    Arogya Koirala
  • Derrick Laurel
    Derrick Laurel
  • Andrew Walker Campion
    Andrew Walker Campion
  • Michael Iv
    Michael Iv
  • Akshay Chaudhari
    Akshay Chaudhari
  • David B. Larson
    David B. Larson

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